CANCER

Does Progesterone cause Cancer?

Many, including state authorities, mistakenly believe that progesterone and synthetic progestins are identical; however, they are not. This misunderstanding is at the core of the misinformation suggesting that natural progesterone presents a cancer risk.

It’s natural for many to feel concerned. Carefully review the research papers provided below regarding different types of cancer. Numerous studies indicate that progesterone plays a protective role against hormonal cancer by activating the p53 gene, which is crucial for apoptosis. When this gene is inactive, cells continue to proliferate.

The hormone estrogen is a known initiator of heart disease and cancer, progesterone inhibits the production of estrogen.

Numerous research studies highlight the protective effects of progesterone in the body. It guards against hypertension, reduces blood lipids, and counteracts coronary hyperactivity—an indicator of coronary artery disease. Additionally, progesterone does not elevate the risk of breast, endometrial, or ovarian cancers and may even offer protective benefits against these conditions. It can also help prevent epilepsy, alleviate vasomotor symptoms, and reduce the likelihood of miscarriages, among other benefits.

Here is some information that will enhance your understanding of the role of progesterone in relation to cancer.

Cancer of hormonally sensitive tissue

Growing evidence indicates that 95% of cancers stem from environmental factors, including pollutants from agriculture and industry, processed foods, and the inappropriate use of prescription drugs like estrogen, while merely 5% are linked to our genetic makeup.

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A multitude of studies indicates that we have the ability to modify gene expression by altering the factors that influence them, including those previously mentioned. Ongoing research, which began in the 1990s, has pinpointed several genes that play a pivotal role in regulating cell growth through the production of substances that control cell division. When these genes are harmed by pollutants, oxidation, or insufficient nutrients, it can lead to rapid cell proliferation, ultimately resulting in cancer.

Homocysteine (H) is recognized as a reliable indicator of low levels of specific B vitamins and may signal an increased risk for over fifty common diseases, including cancer. Recent evidence suggests that elevated H levels negatively impact the rate of tumor growth.

A 2002 study on cancer discovered a rise in cancer cases linked to insufficient UV-B exposure and vitamin D3 levels. The researchers assert that mortality rates could decrease with mindful sun exposure and the inclusion of vitamin D3 supplements in one's routine.

It is now acknowledged that if a mother encounters elevated levels of natural or xeno-estrogens during pregnancy, the developing fetus may be impacted, resulting in breast, ovarian, and endometrial cancers in women, as well as testicular, prostate, and increasingly breast cancers in men.

Studies indicate that prolonged exposure to a woman's natural estrogen, typically associated with an extended reproductive lifespan, significantly increases her risk of developing cancer. Additionally, women with diminished progesterone levels face a 5.4 times higher risk of breast cancer, along with a tenfold increase in the likelihood of succumbing to all forms of cancer. Furthermore, the recurrence of breast cancer after a mastectomy is more probable when the surgery is executed during the first half of the menstrual cycle, where estrogen predominates, compared to the latter half.

The contraceptive pill elevates the risk of developing cervical cancer; the longer it is taken, the higher the risk becomes.

HRT (hormone replacement therapy), when not countered by progesterone, is linked to an increased risk of endometrial cancer. Two studies published in 1995 revealed that women who had undergone HRT for over five years had a 32% higher likelihood of developing breast cancer; this risk surged to 41% when combined with a progestin. For postmenopausal women, the risk escalated to 71%, while the likelihood of developing ovarian cancer rose by 72%.

The most recent findings indicating that estrogen and progestin may pose risks for women originated from the Women's Health Initiative, which was concluded three years early in 2003 due to a rise in cases of breast cancer, heart disease, and strokes. In response, the FDA has mandated that pharmaceutical companies place a warning label on hormone replacement therapy (HRT) packaging to denote this increase. By 2004, the estrogen-only segment of the WHI was also terminated due to a reported uptick in stroke incidents.

Tamoxifen, A weak estrogenic medication utilized in breast cancer treatment is categorized as a carcinogen, which leads to a rise in the incidence of both endometrial and liver cancers.

Dr Carole Baggerly is a breast cancer survivor. Her video on how Vitamin D3 helped her is very informative and worth viewing - see here. 

There exists a direct link between low levels of progesterone and the occurrence of cancers affecting the prostate and testes. Alarmingly, our water supply is now tainted with estrogen from hormone replacement therapies (HRT) and contraceptive pills, along with contributions from industrial sources. As a result, men are increasingly exposed to elevated levels of estrogen, correlating with a rise in estrogen-related cancers, including those of the testes and prostate. Additionally, men undergoing estrogen treatment for prostate cancer or after gender-affirming surgery face a higher risk of developing breast cancer. With advancing age, men become more susceptible to estrogen dominance, which leads to a reduction in testosterone levels and an increase in dihydrotestosterone. This hormonal imbalance is associated with decreased libido and a heightened risk of developing prostate hyperplasia or cancer.


There are at least 40 carcinogens to which we are exposed daily. A particular concern are the following:


  • alcohol
  • artificial sweeteners
  • bleaches used for whitening flour etc
  • charred food e.g. toast and browned meat
  • chlorine in drinking water
  • fluoride
  • food preservatives
  • all mineral oil, including liquid paraffin
  • estrogen and xeno-estrogens
  • pesticides
  • industrial chemicals such as dioxin
  • PCB's and phthalates
  • plastics
  • radiation from the sun
  • nuclear power stations
  • TV sets
  • computers and cell phones
  • refined cooking oil and margarine
  • tobacco smoke
  • vehicle exhaust fumes
  • x-rays


Administer a daily dose of 100-200mg of progesterone, or 3-6ml of Natpro. Adjustments may be necessary; use according to symptoms.  In cases where radiation therapy is required, apply the cream directly to the affected area, as it possesses calming, pain-relieving, and regenerative qualities. Progesterone also offers neuroprotection, inhibiting lipid peroxidation and providing vascular benefits. As an anti-inflammatory agent, progesterone has demonstrated the ability to diminish the activity of natural killer cells and other known inflammation triggers.

There is mounting evidence that many - 80 at the last count - if not all our modern diseases, syndromes and symptoms are possibly linked to a vitamin D deficiency, CANCER is one of them. It is extremely important that you have your vitamin D3 level tested. Please visit Benefits of Vitamin D3 and Vitamin D Society. 

This excellent video of Dr Bruce Lipton who is one of the discoverers of epigenetics. He explains that it is possible to change the way a gene expresses itself via nutrition and our minds. Vitamin D3 being of extreme importance. The video is long but well worth the view. See here.


The following nutrients are essential:


  • a high level of all the anti-oxidants:
  • 25,000 IU vitamin A
  • 1-5gm vitamin C
  • 100-1000 IU vitamin E
  • 50mg zinc and, in particular
  • 200-300mcg selenium, which has been found to decrease the risk of getting cancer by nearly 50%, probably because it activates gene p53
  • 100-1000mcg vitamin B12
  • 400-1000mcg folic acid
  • 50-100mg vitamin B6
  • 1 to 5gm L-glutamine
  • 500mg N-acetylcysteine
  • 500mg glutamic acid
  • 500mg glycine
  • 500mg methionine
  • 15 to 60ml Omega 3 flax oil
  • 100mg Co enzyme Q10
  • 1-10gm MSM (methylsulfonyl-methane)
  • SOD (superoxide dismutase) as directed, (this is an extremely expensive and relatively unstable compound)
  • carotenoid complex (as directed on label)
  • milk thistle (as directed)
  • probiotics (as directed)
  • digestive enzymes (as directed)


Research indicates that adhering to the aforementioned guidelines and incorporating natural cancer supplements can potentially lower the risk of developing cancer by as much as 70%. The phytochemicals present in specific plants have proven to be so advantageous that, in some instances, they have prompted cancer cells to return to their original, healthy condition.

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