FIRST TIME USERS

What to expect when using NATPRO Progesterone Cream for the First Time

VITAMIN D3 is vital as it is connected to every single functioning cell and its formation in our bodies. A deficiency reduces the benefits of progesterone, see here and here. If you are deficient it will take progesterone longer to work, and in most cases, it simply does not work. It is so important to get your level up as per the link provided. Please have a vitamin D3 test done. Equally important is Magnesium.

Understanding and being aware of specific symptoms that may arise during your first use of progesterone cream is crucial. These symptoms can also manifest when switching to a different brand of progesterone, as your body needs time to adjust. Typically, this adjustment period should last only a few days; if not, it may indicate that progesterone is not being applied correctly. The body generally takes 2-6 months to fully adapt and allow progesterone to establish itself as the dominant hormone, which is essential. Please refer to the section on How to use Natpro Progesterone Cream for further guidance.

A frequently posed question is, "What happens if I use too much?" In short, nothing adverse occurs, but excessive use of progesterone over an extended period is unnecessary if it's not warranted. Typically, a dosage of 100-200mg per day suffices; however, individuals with severe symptoms may require more at the outset. For instance, those experiencing hot flushes may need 400-500mg daily for 4-6 days or until the symptoms subside, after which the dosage can be gradually reduced. The body naturally produces significant amounts of progesterone during pregnancy, but this high production does not persist afterward. Patients with postpartum depression (PND) and psychotic symptoms may receive 2400mg daily, while those with traumatic brain injury (TBI) may get 1400mg, both under medical supervision, often necessitating hospitalization. It's essential to use at between 100-200mg per day to prevent symptoms of Estrogen Dominance caused by excess estrogen and environmental toxins, with higher initial dosages often required. Once symptoms have fully resolved, the cream dosage can be decreased to no less than 100mg per day. The commonly recommended doses of 20-40mg daily are insufficient and can exacerbate issues by stimulating estrogen receptors. Research consistently indicates that the body responds more favourably to higher dosages, while lower amounts can worsen symptoms by aggravating the estrogen receptors. This may lead to the misconception that progesterone is ineffective, which is misleading. If progesterone is not administered correctly, it simply will not work.

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The late Dr. Katharina (Kittie) Dalton successfully prescribed 2400mg per day for individuals experiencing PND and psychotic-like symptoms, while recommending 800mg for those struggling with nausea. Patients with TBI are typically administered 1400mg daily.

A frequently asked question is, "How long will it take before I see a difference?" This is a challenging question to answer because it's crucial to recognize that any natural product is not a 'quick fix.' Results require time, and patience is essential. Often, symptoms may worsen before they start to improve. Some individuals expect to feel better after just 2-3 days of use, but that’s a misconception. Positive changes may take anywhere from 2 to 6 months, or even longer, depending on the level of excess estrogen present. It’s vital to use the appropriate amount of progesterone based on your symptoms. For females, it’s important to never use less than 100mg/3ml per day, while men may require a lower dose, which also depends on their symptoms. Often, a higher dosage might be necessary to target specific symptoms. Using too little or discontinuing progesterone will likely cause symptoms to return. To maintain stable progesterone levels, it should be applied at least twice a day, as hormone levels begin to decline after 12 hours.

When beginning progesterone therapy, it’s recommended to apply the cream daily for a duration of 2 to 6 months to help regulate and balance the body, while also addressing those distressing symptoms associated with estrogen dominance. The exact length of time required may vary depending on the level of excess estrogen present. Many women seek progesterone because they experience irregular cycles, heavy or persistent bleeding, clotting issues, or simply hormonal imbalances. However, if your cycle is irregular, it’s challenging to apply the cream in sync with it. That’s why consistent daily use for 2 to 6 months is crucial until your cycle normalizes and your symptoms diminish. For those with regular cycles, using the cream for the same duration is still advisable, as it supports the body in adjusting and allows progesterone to take precedence. It’s important to note that even switching from one brand to another can cause disruptions; therefore, it’s essential to remain consistent. As long as the cream is used correctly, the body will soon stabilize.

Individuals respond differently to various stimuli; what may provoke discomfort for one person may not affect another at all. You might experience 'adverse' symptoms commonly seen in both men and women with naturally elevated estrogen levels or, in the case of women, those undergoing HRT (hormone replacement therapy) or taking the BCP (Contraceptive Pill) for an extended period, leading to reduced progesterone levels. In certain instances, you may experience:

  • aches and pains in your joints or anywhere on the body
  • water retention
  • weight gain
  • heart palpitations or a tight chest
  • headaches
  • change in sleep pattern
  • acne
  • and more, in fact any strange adverse symptom

Please continue using the progesterone cream and resist the urge to stop, as these discomforting symptoms will diminish when applied correctly. We are now receiving feedback from women utilizing up to 400mg/12ml at the outset, indicating that it helps them avoid these negative effects commonly referred to as ESTROGEN DOMINANCE symptoms. If the dosage of 100mg/3ml - 200mg/6ml isn't effective for you, consider increasing it until you discover a suitable level, and once you feel stable, you can gradually decrease to a more comfortable dosage. Those experiencing hot flashes and night sweats should aim for a daily intake of 400-500mg for 5-6 days, increasing further if symptoms are particularly severe, as this is the most effective method for alleviating hot flashes and related issues. Once you notice improvements, you can begin to taper down the dosage.

Men may also encounter symptoms of estrogen dominance when they begin using progesterone, with some developing 'man boobs.' However, men do not require excessively high doses. Amount of men - between 10-100mg per day progesterone, more if severe symptoms are experienced. Unless there are specific issues like prostate problems that necessitate a higher amount.

How to Reduce NATPRO Progesterone Cream

You can slowly start to reduce the amount of cream used once you feel stable enough to do so and ALL your adverse symptoms have cleared. It is vital that this is done SLOWLY - if too much is reduced too soon, your symptoms will return. Should this happen, simply increase the amount of cream until you feel stable again and then try again by slowly reducing. It is essential to reduce over a few weeks to prevent adverse symptoms from returning.

How to Reduce - reduce by no more than 16-20mg at a time. Stay on the reduced amount for a week before reducing again. Continue reducing until you find a level that suits you. Symptoms will return if you reduce by too much and too quickly. Never reduce to less than 100mg/3ml per day as all adverse symptoms will return. 

As you start using progesterone, it will slowly become the predominant hormone, which is essential. As this transition occurs, symptoms will begin to alleviate.

You may be estrogen dominant if you encounter several of the symptoms mentioned below. It’s worth noting that men can also experience these symptoms, apart from the obvious female problems.

  • aches and pains
  • anger
  • bleeding which comes either earlier or later than usual in your monthly cycle
  • bloating/weight gain due to water retention
  • breast tenderness
  • bruising
  • constipation
  • dizziness
  • headaches
  • heart palpitations
  • hot flushes
  • hypoglycaemia
  • increased appetite/cravings
  • irritation
  • migraines
  • mild depression
  • mood swings
  • muscle weakness
  • nausea
  • skin problems/acne/melasma
  • spotting
  • tiredness/chronic fatigue

It's advisable to start with a higher dose when first using progesterone to prevent symptoms of estrogen dominance; you can gradually reduce the dosage thereafter. Keep in mind that the goal is to ensure progesterone becomes the dominant hormone.

When using progesterone cream for the first time, please adhere to the following guidelines. The cream can be applied freely all over your body, including your face. For vaginal dryness and inflammation, apply it internally at night, as it's highly effective and is well absorbed by hair follicles. Should you experience any aches or pains, massage the cream directly onto the affected area since progesterone acts as a powerful anti-inflammatory. Personally, I've applied it to my tongue to alleviate occasional burning sensations, and it has proven to provide relief. When selecting a progesterone cream, remember that thicker formulations take longer to absorb. Always scrutinize the ingredients in any product you choose, as many creams may contain parabens and synthetic chemicals, which are best avoided.

Please note: The information below showing quantities of progesterone cream are based on a concentration of 3.33%. 

Women

Men

Use from 10 - 100mg/ 0.3 - 3ml per day. It is best to use the cream twice a day. More may be needed depending on symptoms.

Kindly take a moment to read How to use NATPRO Progesterone Cream to gain a comprehensive understanding of its functionality! Additionally, you will discover a chart that illustrates the duration a tube or dispenser will last based on various usage amounts, along with conversions for teaspoons (metric), milligrams, and milliliters.

Failing to adhere to the instructions above will render it ineffective, leading you to believe that you are squandering your time and money, which is completely unfounded. Correct usage of progesterone is essential.

Tips:

  • When your tube is finished, please cut it open as there is usually quite a bit of cream left behind. This cream is simply too valuable to throw away
  • Progesterone cream is the best delivery method as 96% gets destroyed by the gut and liver if using oral progesterone - see here
  • Natpro is the best lubricant ever! It helps with inflammation as well as vaginal atrophy and dryness which so many women suffer from when going into menopause. 
  • Use Natpro Progesterone cream as a facial moisturiser
  • It is EXCELLENT as an underarm deodorant - magnesium oil is even better
  • Excellent on burns and insect bites etc and bruising - in fact any skin irritation
  • Please read references given on each page

BEFORE USING PROGESTERONE CREAM FOR THE FIRST TIME, PLEASE READ THE LINk ON ESTROGEN DOMINANCE

  1. Menstruating - If a regular cycle is observed, apply cream twice daily from ovulation for the following 14 days; bleeding should occur within one to two days. The luteal phase consistently lasts 12-14 days for all women; anything shorter is classified as a 'defective luteal phase.' Cycle lengths can range from 21 to 36 days. For instance, in a 21-day cycle, the cream should be applied starting on day 8 for 14 days; in a 28-day cycle, begin on day 15 for 14 days, and in a 36-day cycle, start on day 22 for 14 days. Use 100-200mg/3-6ml daily, with possibly more required based on symptom severity.
  2. Peri or Post Menopausal, Hysterectomy, Oophorectomy, Pre-pubertal, Pubertal - iIf there is no cycle, or if it is inconsistent and too challenging to monitor, consider using 100-200mg/3-6ml, possibly more based on the severity of the symptoms, EVERY DAY without interruption. Do not be concerned about any bleeding, spotting, or clotting that may arise. Contrary to some suggestions, there is no need to take breaks, though some women may choose to do so, but they typically end up using it daily without pauses. When the cycle is irregular, tracking it becomes quite difficult.
  3. Severe symptoms - Hot Flushes use at least 400-500mg per day for 4-6 days generally stops them. It is best to apply the cream hourly. Heavy/clotting/continual bleeding  use 400-600mg per day for 2-6 months, ignoring the cycle. When the bleeding has stopped, slowly reduce the cream until bleeding occurs again, then discontinue the cream for 14 days. Then start using the cream again from day 15 for 14 days. Over the coming months the natural cycle length will assert itself. It is best to apply the cream hourly. A multitude of adverse symptoms use a minimum of 200mg/6ml per day following the cycle, more cream may be needed. If symptoms return during the break, then continue applying the cream twice a day or more frequently until they resolve. Once they have, then begin to follow your cycle again.
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